As a key pharmaceutical intermediates of Bromobenz Compounds , we open the south American market through the strong network of CHEMO group.
The Bromobenz Compounds is made from Bromotoluene by the following reaction:
In the light conditions, the bromine was added dropwise from the surface to 105 ℃ of the bromine toluene was added dropwise at a temperature of pre 105-110 ℃. The temperature of post 135 ℃. After the addition the temperature gradually rose to 150 ℃, calcium carbonate powder and then add water, stir, heated at reflux for 15min for hydrolysis. Then steam distillation, the distillate was cooled, filtered Bromobenz Compounds  crystallization.